Xie Group FOR Genetic Circuit Engineering

Tsinghua National Lab - Bioinformatics Division - Center for Synthetic and Systems Biology

Welcome to Our Laboratory!

Our goal is  to construct synthetic molecular systems to study complex biological phenomena, and to engineer genetic circuits for manipulation of cells, especially mammalian cells in a non-destructive way. Specifically, we are interested to link molecular information processing with cellular decision making and apply this technology platform to addressing key challenges in biomedical and biotechnology applications. Our major research areas:
  • Construction of parts and motifs for synthetic biology research
  • Automation for gene synthesis and genetic circuit assembly
  • Genetic circuit engineering for gene therapy and cell-based therapy
  • Integrative biomolecular sensing and processing for cellular automation