清华合成与系统生物学中心
Tsinghua Center for Synthetic and Systems Biology
liuxiao
刘晓(Xiao Liu)
PI,博导
生命科学学院,“青年千人计划”获得者





联系方式
清华大学生命科学学院,北京,100084,中国
E-mail: xiaoliu2@stanford.edu
教育背景及工作履历
1994       南京大学生物系   学士
1997       北京大学细胞遗传系 硕士
2005       约翰霍普金斯医学院生物物理系 博士
2011   斯坦福大学发育生物学系 博士后
2012−至今   清华大学 生命科学学院 PI,博导

主要研究领域与方向

实验室主要通过开发和利用高通量实验技术,从功能基因组学和系统生物学角度,主要以线虫神经系统为模型,研究细胞命运决定和进化的分子机制 。
主要论文
1. Liu, X., Long, F., Peng, H., Aerni, S.J., Jiang, M., Sánchez-Blanco A., Murray. J.I., Preston, E., Mericle, B., Batzoglou, S., Myers, G., and Kim, S.K. (2009). Analysis of cell fate from single-cell gene expression profiles in C. elegans. Cell 139: 623 - 633
2. Long, F., Peng, H.,
Liu, X., Kim, S.K., and Myers, G. (2009). A 3D digital atlas of C. elegans and its applicationto single-cell analyses. Nature Mathods 6: 667 - 672
3. Long, F., Peng, H.,
Liu, X., Kim, S.K., and Myers, G. (2008). Automatic Recognition of Cells (ARC) for 3D images of C. elegans. Recomb.
4. Peng, H., Long, F., Liu, X., Kim, S.K., and Myers, E.W. (2008). Straightening Caenorhabditis elegans images. Bioinformatics 24, 234-242
5.
Liu, X., C.K. Lee, N.D. Clarke, and J.D. Lieb (2006) Quantification of chromatin contributions to DNA-binding site utilization. Genome Res. 16: 1517 – 1528
6.
Liu, X., Noll, D.M., Lieb, J.D., and Clarke, N.D. (2005) DIP-chip: Rapid and accurate determination of DNA-binding specificity. Genome Res. 15: 421 – 427
7.
Liu, X. and Clarke, N. D. (2002) Rationalization of gene regulation by a eukaryotic transcription factor: calculation of regulatory region occupancy from predicted binding affinities. J. Mol. Biol. 323:1-8.
8. Linask, K.K., Ludwig, C., Han, M., Liu, X., Radice, G.L. & Knudsen K.A. (1998) N-Cadherin/Catenin Mediated Morphoregulation of Somite formation. Developmental Biology 202, 85-102.
9. He, W., Gao, J., Liu, X., & Sun, F. (1996) Establishment of Embryonic Stem Cell Lines Derived from Outbred Mouse Embryos and Production of Chimeras. Chinese Journal of Developmental & Reproductive Biology 5, 21-24.

Honors and Fellowships
2007 Larry L. Hillblom Foundation Posdoctoral Fellowship
2005 Phi Beta Kappa



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