Speaker: Prof. Hyunju Lee, Ph.D, School of Info. & Comm., GIST, South Korea
Host: Dr. Rui Jiang, Bioinformatics Division, TNLIST; Dr. Ting Chen, Bioinformatics Division, TNLIST
ABSTRACT: This talk consists of two main parts. First, integrative approaches for the analysis of DNA copy number aberrations (CNAs), gene expressions, protein-protein interactions in cancer are introduced. To find cancer-related genes and pathways, we developed a voting-based cancer module identification method by combining topological and data-driven properties, and a wavelet-based method to distinguish cancer-driving genes from passenger genes. In the second part of the talk, a disease gene search engine, DigSee, is introduced. DigSee is a Web service to search MEDLINE abstracts for evidence sentences describing that ‘genes’ are involved in the development of ‘cancer’ through ‘biological event. DigSee is available through http://gcancer.org/digsee.
时间：2013年10月24日（星期四）上午 11:00 – 12:00