Epigenetics, known as heritable factors on gene expression that are not directly coded in DNA sequences, has been found to be an important part of the complicated molecular regulation systems in cells. Genome-wide observations on major epigenetics factors like DNA methylation, histone modification and nucleosome structure are emerging, raising many new questions to bioinformatics research in epigenetics or computational epigenetics study. Our current efforts focus on possible associations between genomics factors and epigenetics factors, as a step toward the final understanding of systems that involves both genetic and epigenetic factors.
- Gene Expression and Transcriptional Regulation
- RNA Regulation: miRNA and beyond
- Alternative Splicing
- High-Throughput Omics Data Mining
- Genetic Polymorphism & Complex Diseases
- Bioinformatics in Epigenetics
- Computational Systems Biology
- Traditional Chinese Medicine and Systems Medicine
- Synthetic Biology
The mission of our Division and Center is to pursue excellence in scientific research and education on fundamental questions in life science with informatics and systems approaches, on theoretical and methodological questions therein for information science and technology, on the informatics mechanism of life systems, and on the engineering of molecular regulatory systems.
Tsinghua Campus Tour